Friday, October 22nd, at 11:15 a.m., Professor Brian Strahl, Professor and Interim Chair of Biochemistry and Biophysics, UNC Chapel Hill, will discuss Epigenetics and the Histone Code or “Things Mom Didn’t Have to Teach Me.” (Title line above abbreviated for impact.) We will meet over Zoom and the Zoom link will be emailed to current members. If you are a previous member or are on our mailing list, email firstname.lastname@example.org for the Zoom link.
Each cell in our body contains ~3.4 billion base pairs, which, if stretched out from end to end, would be 6 ft in length, but somehow fits into a cell nucleus only about 10 μm (~0.00001 yards) in diameter. How our DNA is packaged into the nucleus and then unwound for gene expression and protein synthesis (both critical to cell identity and fetal development) is still poorly understood. Brian Strahl, co-Director of the UNC Program in Chromatin and Epigenetics, is at the forefront of deciphering how DNA is packaged and then unwound for expression. DNA packaging and unwinding is largely mediated by a class of proteins called histones. Brian’s lab has been studying these proteins and the small chemical additions that occur on them or they make to DNA (e.g., adding or deleting phosphate or methyl groups).
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